Seasonality Modifies Methylation Profiles in Healthy People

Seasonality Modifies Methylation Profiles in Healthy People

DNA methylation is a well-characterized epigenetic modification that plays an important role in the regulation of gene expression. There is growing evidence on the involvement of epigenetic mechanisms in disease onset, including cancer. Environmental factors seem to induce changes in DNA methylation affecting human health. However, little is known about basal methylation levels in healthy peopl...

DNA methylation profiles in preeclampsia and healthy control placentas.

Preeclampsia is a hypertensive disorder of pregnancy that affects 3-5% of all pregnancies. There is evidence to suggest that epigenetic mechanisms, such as DNA methylation, play a role in placental development and function. This study compared DNA methylation profiles of placentas from preeclampsia-affected pregnancies with placentas from healthy pregnancies to identify gene-specific changes in...

Healthy buildings, healthy people

When researcher Melkam Kebede started her five-year fellowship at the Charles Perkins Centre at the University of Sydney, Australia, she was struck by the abundance of natural light and design features that encouraged people to move and mingle. “I’ve worked in many places before, but never seen laboratories with so much natural light,” says Kebede, whose research is on the links between type 2 ...

Paying People to Be Healthy

User Financial Incentives (UFIs) have emerged as a powerful tool for health promotion. Strong evidence suggests that large enough incentives paid to individuals, conditional on behaviour they can control, encourages more of the desired behaviour. However, such interventions can have unintended consequences for non-targeted behaviours. Implementation difficulties that result in individuals not u...

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